Popular answers (1) Although we routinely use UV lamps inside our biosafety cabinets and assume that UV light does not penetrate through matter, there are many reports that suggest this might not
UV-C rays can affect materials both on a physical and chemical level. With excessive exposure to UV radiation, materials can lose their strength, become less flexible, fade in color, and crack. Some types of material are more susceptible to UV-C than others. UV-C light can affect many synthetic and natural polymers, including neoprene UV can travel well through plastic, but not through silicate-based glass. Radio waves can travel through brick and glass, but not well through a metal box. Each of these differences has a slightly different answer, but each answer is based on molecular resonance or crystalline structure (or lack thereof) or electrical conductivity.
Ultraviolet light can pass through glass, but the amount and type of UV (eg UVA, UVB etc) transmitted depends on the type and thickness of the glass, any coatings and laminates. Does UV pass
However, what Plexiglas does regarding ultraviolet light is reduce its intensity. As ultraviolet rays pass through Plexiglas windows, they're refracted and broken up, made less intense so that those on the other side of the window aren't exposed to the full level of the radiation. Bubbling, Peeling and Cracking

Check a fabric’s sun safety by holding it up to the light. If you can see through, UV radiation can easily penetrate the fabric and reach your skin. Tight clothing can stretch and reduce the level of protection offered, as the fibers pull away from each other and allow more UV light to pass through. How does UV light effect microorganisms?

Standard window glass, according to the International Ultraviolet Association, allows UVA to pass through while almost 100% of the UVB and UVC light is blocked. In other words, while it can be safe to stare at a UVC lamp through a glass or window, it's not recommended to do so.
Clear-transparent PLEXIGLAS® products show the highest transmittance, of up to 92 percent, in the visible range. The reduction is due only to a physical reflection loss of 4 percent at each of the light entry and exit surfaces; the material itself allows light to pass through unhindered. PLEXIGLAS® is thus one of the most transparent We strongly recommend that anyone using UV light to disinfect equipment, surfaces, or air, follow all recommended health and safety precautions and to avoid direct exposure to UV light. In summary: UV-C radiation of skin, eyes, or any body part should be avoided. Always wear appropriate PPE when handling un-shielded UV-C radiation sources (e.g A photon that's 10.2 eV has a wavelength of $1.21\times10^{-7} m$, which is UV light. Less energetic light (e.g. blue-to-red) just doesn't have enough energy to kick up that electron. So the photons pass through because they can't be absorbed.

Table of Contents (click to expand) Photochromic glasses work by containing specialized optical lenses called photochromic lenses. These lenses automatically darken in the presence of certain types of light, usually ultraviolet light, and become clear again in the absence of that light. Photochromic glasses may be made of different materials

Material Transparency to UVC This Stanford University source reveals that short wave UV (UVC) cannot pass through most plastics or ordinary glass. Most acrylic plastics do not allow UV-C wavelengths (100-280 nm) to penetrate. Also, very thin acrylic sheets of below 5 millimeters do not let UVC light penetrate. If you click on my signature banner, you can go download the free PDF version of my book, which includes a chapter on lighting for turtles, and an appendix on UV-B. But to answer your question succinctly, no, UV-B doesn't penetrate most acrylic sheets well, and plexiglass is a form of acrylic. There are special forms of acrylic available that The World Health Organization (WHO) has issued a stern warning against people using UV light to sterilise their hands or any other part of their skin. During the White House briefing on Thursday RLsK.
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